The Problem

The Consequence

Uncontrolled bleed propagation

in almost 50% of seriously injured patients

Leads to death almost inevitably

The Solution

Rapidly

Effectively

Save lives

An Engineered Factor Va Prevents Bleeding Induced by Anticoagulant wt Activated Protein C
Improved hemostasis in hemophilia mice by means of an engineered factor Va mutant
New understandings of post injury coagulation and resuscitation
Cause of trauma-induced coagulopathy